Desvenlafaxine succinate, the succinate salt form of the isolated major active metabolite of Venlafaxine (HY-B0196), is an orally active and BBB penetrated 5-HT and norepinephrine reuptake inhibitor, with IC50 values of 47.3 nM and 531.3 nM for hSERT and hNET, respectively. Desvenlafaxine succinate (DVS) shows weak binding affinity (62% inhibition at 100 µM) at the human dopamine (DA) transporter[1][2].
Molecular Weight:
381.46
CAS Number:
[448904-47-0]
Formula:
C20H31NO6
Target:
Serotonin Transporter
Application Notes:
MCE Product type: Reference compound1
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