GQN-B37-E is a potent selective binder and inhibitor of MCL-1. GQN-B37-E binds to the BH3-domain-binding pocket in MCL-1. GQN-B37-E exhibits binding affinity for MCL-1 at the submicromolar range (Ki = 0.6 µM) without apparent binding to BCL-2 or BCL-XL[1].
Molecular Weight:
526.97
CAS Number:
[2982663-28-3]
Formula:
C29H23ClN4O4
Target:
Bcl-2 Family
Application Notes:
MCE Product type: Reference compound
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