PHTPP-1304 is a PHTPP-based autophagy targeting chimera (AUTOTAC). PHTPP-1304 induces the degradation of estrogen receptor ERbeta through the autophagy pathway, rather than ubiquitination (DC50 ~ 2 nM, in HEK293T cells, p62. PHTPP-1304 can be used to study various cancers mediated by ERbeta[1].
Molecular Weight:
944.96
Purity:
99.96
CAS Number:
[2410081-60-4]
Formula:
C51H50F6N4O7
Target:
Autophagy,AUTOTACs,Estrogen Receptor/ERR
Application Notes:
MCE Product type: Reference compound
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