PBA-1105 is an autophagy-targeting chimera (AUTOTAC) that induces p62 self-oligomerization. PBA-1105 selectively binds to exposed hydrophobic regions of misfolded proteins, facilitating their degradation via the autophagic pathway. PBA-1105 increases the autophagic flux of Ub-conjugated aggregates[1].
Molecular Weight:
640.81
Purity:
99.47
CAS Number:
[2410081-56-8]
Formula:
C39H48N2O6
Target:
Autophagy,AUTOTACs
Application Notes:
MCE Product type: Reference compound
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