Anle138b-F105, CAS [[2941386-44-1]]

Catalog Number: MCE-HY-161746
Article Name: Anle138b-F105, CAS [[2941386-44-1]]
Biozol Catalog Number: MCE-HY-161746
Supplier Catalog Number: HY-161746
Alternative Catalog Number: MCE-HY-161746-25MG,MCE-HY-161746-10MG,MCE-HY-161746-5MG
Manufacturer: MedchemExpress
Category: Biochemikalien
Anle138b-F105 is an autophagy-targeting chimera (AUTOTAC) that targets p62/Sequestosome-1/SQSTM1. Anle138b-F105 binds to the ZZ domain of p62, induces conformational activation, self-oligomerization, interaction with LC3, and formation of autophagosomes. Anle138b-F105 induces autophagic flux of ubiquitin-conjugated aggregated proteins, leading to their lysosomal degradation. Anle138b-F105 is applicable for the research of neurodegenerative proteinopathies[1].
Molecular Weight: 624.70
Purity: 98.59
CAS Number: [2941386-44-1]
Formula: C36H37FN4O5
Target: Autophagy,AUTOTACs
Application Notes: MCE Product type: Reference compound1