HL389 inhibits proliferation of cancer cells MDA-MB-231 and MCF-7, with IC50 of 11.39 µM and 9.66 µM. HL389 can be utilized as the ligand for E3 ligase for the synthesis of PROTAC degrader HL435 (HY-161769)[1].
Molecular Weight:
498.29
Formula:
C22H19BrF3NO4
Target:
Ligands for E3 Ligase
Application Notes:
MCE Product type: Reference compound1
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