HL389-NHC2-PEG3-C2NH inhibits proliferation of cancer cells MDA-MB-231 and MCF-7, with IC50 of 11.39 µM and 9.66 µM. HL389-NHC2-PEG3-C2NH can be utilized as a conjugate of an E3 ligase ligand and a linker, for the synthesis of PROTAC degrader HL435 (HY-161769)[1].
Molecular Weight:
644.48
Formula:
C28H33BrF3N3O6
Target:
E3 Ligase Ligand-Linker Conjugates
Application Notes:
MCE Product type: Reference compound1
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