P-gp/CDK2-IN-1 (Compound 4j) is an inhibitor for is inhibitor for P-glycoprotein (P-gp) and for cyclin-dependent kinase-2 (CDK2). P-gp/CDK2-IN-1 inhibits the proliferation of cancer cells SW-480 and MCF-7 wit IC50 of 38.6 µM and 26.6 µM. P-gp/CDK2-IN-1 exhibits antioxidant efficacy with EC50 of 580 µM in DPPH experiment[1].
Molecular Weight:
417.41
Formula:
C21H23NO8
Target:
CDK,P-glycoprotein
Application Notes:
MCE Product type: Reference compound1
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