EGFR-IN-117, CAS [[3035639-05-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-161785
Supplier Catalog Number:
HY-161785
Alternative Catalog Number:
MCE-HY-161785-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
EGFR-IN-117 (Compound 8h) exhibits inhibitory activity against EGFR mutation, targets the tumor environment, and induces apoptosis of cancer cells. EGFR-IN-117 inhibits proliferations of H1975, PC-9, and EGFR mutant cells BaF3-EGFRL858R/T790M/C797S and BaF3-C797S/Del19/T790M, with IC50 of 13 nM, 19 nM, 1.2 nM and 1.3 nM, respectively. EGFR-IN-117 exhibits antitumor efficacy in mouse models[1].
Molecular Weight:
572.52
CAS Number:
[3035639-05-2]
Formula:
C25H30BrN7O2S
Target:
Apoptosis,EGFR
Application Notes:
MCE Product type: Reference compound
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