Bcl-2-IN-20 (Compound 81) is an inhibitor for Bcl-2 with IC50 IC50>10 µM), A549 (IC50=6.1 µM), HepG2 (IC50>10 µM), MCF-7 (IC50=8.9 µM), HCT116 (IC50>10 µM) and HEK-293 (IC50=14.1 µM). Bcl-2-IN-20 promotes the ROS production, induces apoptosis and DNA damage[1].
Molecular Weight:
500.32
Formula:
C22H14BrNO6S
Target:
Apoptosis,Bcl-2 Family,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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