G9a-IN-2 (Compound 7i) is an inhibitor for histone methyltransferases G9a with IC50 of 0.024 µM. G9a-IN-2 reduces H3K9me2 levels and induces the mRNA expression of gamma-globin mRNA. G9a-IN-2 shows the potential in ameliorating sickle cell disease (SCD)[1].
Molecular Weight:
522.68
CAS Number:
[2648853-26-1]
Formula:
C30H42N4O4
Target:
Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound
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