SP3N is a specific degrader of the prolyl isomerase (FKBP12). The alkylamine of SP3N is metabolized to a reactive aldehyde (SP3CHO), which recruits the SCFFBXO22 ligase for FKBP12 degradation. SP3N may be used in research for cancer[1].
Molecular Weight:
727.88
Formula:
C39H57N3O10
Target:
FKBP
Application Notes:
Reference compound
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