Antibacterial agent 228 (Compound 8) inhibits the mycobacterial ribosome (IC50 for Mycobacterium smegmatis is 2.31 µM) and exhibits antibacterial activity against M. tuberculosis H37Rv (MIC=2 and 0.25 µg/mL for wildtype and delta1258c mutant), M. abscessus ATCC 19977 (MIC=8 and 8 µg/mL for wildtype and delta2780c mutant) and M. smegmatis (MIC=8 µg/mL)[1].
Molecular Weight:
527.63
Formula:
C26H42FN3O7
Target:
Bacterial
Application Notes:
Reference compound
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