ZXH-8-004 (2-12-2-deg) is a potent DENV E PROTAC degrader with an DC50 value of 0.21 µM. ZXH-8-004 shows exhibit antiviral potencies (Blue: E3 ligase (HY-103596), Black: linker (HY-42149), Pink: DENV E ligand (HY-161807))[1].
Molecular Weight:
861.70
Formula:
C38H33F6N7O10
Target:
Dengue Virus,PROTACs
Application Notes:
Reference compound
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