JWZ-5-13 is a potent CDK7 PROTAC degrader that significantly degrades CDK7 via the ubiquitin-proteasome system. JWZ-5-13 has antitumor activity. (Pink: Target protein ligand (HY-161830), Black: linker (HY-Y0925), Blue: E3 ligase ligand (HY-112078))[1].
Molecular Weight:
983.23
Formula:
C54H66N10O6S
Target:
CDK,PROTACs
Application Notes:
Reference compound
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