(S)-JWZ-5-13 (compound 17-Neg), a PROTAC CDK7 degrader, is a negative control compound of JWZ-5-13 (HY-161828). (S)-JWZ-5-13 displays similar in vitro CDK7 inhibition (IC50 = 21.1 nM) to JWZ-5-13, but fails to induce CDK7 degradation in cells[1].
Molecular Weight:
983.23
Formula:
C54H66N10O6S
Target:
CDK,PROTACs
Application Notes:
MCE Product type: Reference compound
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