LSD1-IN-31 (compound 11e) can directly bind to LSD1/CoREST complex to reduce LSD1 demethylation enzymatic activity. LSD1-IN-31 inhibits LSD1 demethylation activity and influences its downstream IkappaB/NF-kappaB signaling pathway. LSD1-IN-31 inhibits osteoclastic bone loss in vitro and in vivo. LSD1-IN-31 can be used for osteoporosis research[1].
Molecular Weight:
657.47
Formula:
C36H57ClN2O3Si2
Target:
Histone Demethylase
Application Notes:
Reference compound
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