Pim-1 kinase inhibitor 8 is a potent PIM-1 inhibitor with an IC50 value of 14.3 nM. Pim-1 kinase inhibitor 8 impedes cell proliferation and migration through PIM-1 inhibition and the induction of both apoptosis and autophagy. Pim-1 kinase inhibitor 8 inhibits solid tumor growth in Solid Ehrlich Carcinoma (SEC)-bearing mice. Pim-1 kinase inhibitor 8 can be used for breast and liver cancer research[1].
Molecular Weight:
275.30
Purity:
99.90
CAS Number:
[916038-47-6]
Formula:
C14H17N3O3
Target:
Apoptosis,Autophagy,Pim
Application Notes:
Reference compound
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