BKN-1 is a bifunctional ligand that can not only track the formation of mtG4s (G-quadruplexes, four-stranded DNA structures containing Hoogsteen bonds) through far-red emission, but can also induce mitochondrial dysfunction. BKN-1 has anti-tumor activity and may cause mtDNA loss, damage mitochondrial integrity, reduce ATP levels, and trigger ROS imbalance, leading to apoptosis and autophagy[1].
Molecular Weight:
556.48
CAS Number:
[1607831-82-2]
Formula:
C31H29IN2
Target:
Apoptosis,Autophagy
Application Notes:
Reference compound
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