Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels[1][2].
Molecular Weight:
302.7142
Purity:
99.86
CAS Number:
[284490-13-7]
Formula:
C11H15ClN4O4
Target:
Apoptosis,Nucleoside Antimetabolite/Analog
Application Notes:
Reference compound
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