hAChE/hBACE-1-IN-3 (Compound 23a) is a mixed-type inhibitor of hAChE and hBACE-1 with IC50 values of 0.32 µM and 0.39 µM, respectively, Ki values of 0.26 µM and 0.46 µM, respectively. hAChE/hBACE-1-IN-3 can penetrate the blood-brain barrier[1].
Molecular Weight:
421.53
Formula:
C25H31N3O3
Target:
Beta-secretase,Cholinesterase (ChE)
Application Notes:
Reference compound
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