Antitumor agent-130 (Compound 7b) is a p300 histone acetyltransferases (HAT) inhibitor with an IC50 of 1.51 µM. Antitumor agent-130 combinates with doxorubicin (HY-15142A) can significantly inhibit tumor growth and invasion in vitro and in vivo[1].
Molecular Weight:
387.81
Formula:
C20H18ClNO5
Target:
Histone Acetyltransferase
Application Notes:
Reference compound
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