FX-11 is a potent, selective, reversible and competitive lactate dehydrogenase A (LDHA) inhibitor, with a Ki of 8 µM. FX-11 reduces ATP levels and induces oxidative stress, ROS production and cell death. FX-11 shows antitumor activity in lymphoma and pancreatic cancer xenografts[1][2][3].
Molecular Weight:
350.41
Purity:
99.21
CAS Number:
[213971-34-7]
Formula:
C22H22O4
Target:
Apoptosis,Lactate Dehydrogenase,Reactive Oxygen Species (ROS)
Application Notes:
Reference compound
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