Nur77 modulator 3 (9e) can bind to Nur77 and inhibit TGF-beta1-induced alpha-SMA and COLA1 expression in a Nur77-dependent manner. Nur77 modulator 3 induces Nur77 expression and enhances autophagic flux by inhibiting the mTORC1 signaling pathway in vitro and in vivo. Nur77 modulator 3 blocks the progression of hepatic fibrosis[1].
Molecular Weight:
308.40
Purity:
99.01
CAS Number:
[2097787-75-0]
Formula:
C17H16N4S
Target:
Autophagy,mTOR
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
