HNPMI is an inhibitor of EGFR and has cytotoxic effects on tumor cells. HNPMI can downregulate the protein levels of osteopontin, survivin and cathepsin S, leading to apoptosis. HNPMI also regulates BCL-2/BAX and p53 in CRC cell lines to inhibit tumorigenesis[1].
Molecular Weight:
360.41
Purity:
99.57
CAS Number:
[1980848-48-3]
Formula:
C22H20N2O3
Target:
EGFR
Application Notes:
Reference compound
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