COX-2/15-LOX/mPGES1-IN-1 (Compound 2c) is an inhibitor of COX-2, 15-LOX, and mPGES-1 enzymes with IC50 values of 0.057, 2.39, and 2.8 µM, respectively. COX-2/15-LOX/mPGES1-IN-1 possesses anti-inflammatory activity and can inhibit rat paw edema in vivo experiments[1].
Molecular Weight:
352.34
Formula:
C19H16N2O5
Target:
COX,Lipoxygenase
Application Notes:
Reference compound
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