OSM-S-106 is a pro-inhibitor and that inhibition of PfAsnRS occurs via enzyme-mediated production of an Asn-OSM-S-106 adduct. OSM-S-106 inhibits protein translation and activates the amino acid starvation response. OSM-S-106 exhibits selective activity against Plasmodium blood and liver stages and low intrinsic clearance by human microsomes[1].
Molecular Weight:
306.36
Purity:
99.34
CAS Number:
[2650846-59-4]
Formula:
C12H10N4O2S2
Target:
Parasite
Application Notes:
MCE Product type: Reference compound
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