JAK1/2-IN-1 is a potent JAK1 and JAK2 inhibitor with IC50 values of 0.4 nM and 8.1 nM, respectively. JAK1/2-IN-1 also inhibits IL-4 and IL-13 with IC50s of 136.5 nM and 19.1 nM, respectively (WO2023244775A1, Example 33a)[1].
Molecular Weight:
433.19
Purity:
98.36
CAS Number:
[3023876-01-6]
Formula:
C19H19BF3N5O3
Target:
Interleukin Related,JAK
Application Notes:
MCE Product type: Reference compound
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