QC-182 is a potent PROTAC degrader of p300/CBP. QC-182 reduces p300 protein in the SK-HEP-1 cells (DC50 = 93nM). QC-182 potently and effectively inhibits cell growth in the SK-HEP-1 and JHH7 cell lines with IC50 values of 0.733 and 0.477 µM, respectively. QC-182 can be used for the research of hepatocellular carcinoma (HCC)[1].
Molecular Weight:
816.85
Purity:
98.94
CAS Number:
[3032646-96-8]
Formula:
C44H42F2N8O6
Target:
Histone Acetyltransferase,PROTACs
Application Notes:
MCE Product type: Reference compound
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