UCM-13369 (Compound 4b) is a NPM1 inhibitor. UCM-13369 downregulates the pathway associated with mutant NPM1 C+, and specifically recognizes the C-end DNA-binding domain of NPM1 C+. UCM-13369 induces apoptosis in AML cell lines and primary cells, that can be used for the research of AML[1].
Molecular Weight:
389.53
CAS Number:
[2921944-77-4]
Formula:
C25H31N3O
Target:
Apoptosis
Application Notes:
MCE Product type: Reference compound1
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