FAZ-3532 is a G3BP inhibitor (Kd = 0.54 µM) which binds to the NTF2L nsP3 binding pocket in G3BP1. FAZ-3532 disrupts the co-condensation of RNA, G3BP1, and caprin 1. FAZ-3532 inhibits G3BP-driven stress granule formation. FAZ-3532 can be studied as a powerful tool to probe the biology of stress granules and a promising interventions designed to modulate stress granule formation[1].
Molecular Weight:
713.88
Purity:
99.66
CAS Number:
[3036029-72-5]
Formula:
C38H56FN5O7
Target:
DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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