AMPK-IN-5 (compound 7m) is a Osthole (HY-N0054) derivative, and blocks MAPK signal transduction by inhibiting the phosphorylation of JNK and p38, thereby inhibiting the release of inflammatory cytokines. AMPK-IN-5 reduce DSS-induced ulcerative colitis and LPS (HY-D1056)-induced acute lung injury[1].
Molecular Weight:
414.54
Formula:
C24H34N2O4
Target:
JAK,p38 MAPK
Application Notes:
MCE Product type: Reference compound
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