XL44, an hRpn13 binder, induces hRpn13-dependent apoptosis and also restricts cell viability by a PCLAF-dependent mechanism. XL44 induces ubiquitin-dependent loss of hRpn13Pru and ubiquitin-independent loss of select KEN box containing proteins[1].
Molecular Weight:
388.39
Purity:
98.00
CAS Number:
[2637949-91-6]
Formula:
C23H17FN2O3
Target:
Apoptosis
Application Notes:
MCE Product type: Reference compound1
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