NLRP3-IN-33 (Compound 12o) is a blood-brain barrier permeable inhibitor of AChE and BChE, with IC50 values of 1.02 µM and 7.03 µM against hAChE and hBChE respectively. NLRP3-IN-33 possesses antioxidant, anti-inflammatory, and metal chelating activities, making it a potential candidate for research in Alzheimers disease (AD)[1].
Molecular Weight:
393.39
Formula:
C21H19N3O5
Target:
Cholinesterase (ChE),Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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