STAT6-IN-12 is a potent STAT6 inhibitor with an IC50 of 50 nM. STAT6-IN-12 also inhibits Smad2/3 with an IC50 of 68 nM. STAT6-IN-12 inhibits TGFbeta-dependent Smad2/3 signaling pathway, IL-4-dependent STAT6 signaling pathway, and cellular inflammatory responses. STAT6-IN-12 can be used for the research of inflammation[1].
Molecular Weight:
368.81
Formula:
C18H21ClO6
Target:
Interleukin Related,STAT,TGF-beta/Smad
Application Notes:
MCE Product type: Reference compound
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