PTPN2/1-IN-3 (compound 4) is a modified, orally active PTPN2/N1 inhibitor based on ABBV-CLS-484 (HY-145923). PTPN2/1-IN-3 has anti-tumor effects, inhibiting PTPN2 with an IC50 of 9.3 nM and having an oral bioavailability of 93% in mice[1].
Molecular Weight:
343.37
Purity:
99.89
Formula:
C14H18FN3O4S
Target:
Phosphatase
Application Notes:
MCE Product type: Reference compound
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