cGAS-IN-3 (compound 30d-S) is an orally active cyclic GMP-AMP synthase (Cyclic GMP-AMP Synthase/cGAS) inhibitor with good plasma exposure and low clearance. cGAS-IN-3 has anti-inflammatory activity and can significantly reduce lung inflammation in rats[1].
Molecular Weight:
469.31
Formula:
C21H20Cl2F2N4O2
Target:
Cyclic GMP-AMP Synthase
Application Notes:
MCE Product type: Reference compound1
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