ERK1/2 inhibitor 10, CAS [[3056077-07-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-162460
Supplier Catalog Number:
HY-162460
Alternative Catalog Number:
MCE-HY-162460-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
ERK1/2 inhibitor 10 (Compound 36c) is a potent ERK1 and ERK2 inhibitor (IC50: 0.11 and 0.08 nM respectively). ERK1/2 inhibitor 10 inhibits ERK1/2 and blocks the phosphorylation expression of their downstream substrates p90RSK and c-Myc. ERK1/2 inhibitor 10 induces cell apoptosis and incomplete autophagy-related cell death. ERK1/2 inhibitor 10 shows potent antitumor efficacy against triple-negative breast cancer and colorectal cancer models harboring BRAF and RAS mutations[1].
Molecular Weight:
465.96
CAS Number:
[3056077-07-4]
Formula:
C23H20ClN5O2S
Target:
ERK
Application Notes:
MCE Product type: Reference compound1
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