Tyrosine kinase-IN-8 (compound 4e) is a BCR-ABL1 tyrosine kinase inhibitor (TKI). Tyrosine kinase-IN-8 shows anti-proliferative activity against K562 cells, a chronic myeloid leukemia (CML) cell line (CC50=0.8 µM). Tyrosine kinase-IN-8 can be used in the study of chronic leukemia[1].
Molecular Weight:
561.54
Formula:
C31H21F2N7O2
Target:
Bcr-Abl
Application Notes:
MCE Product type: Reference compound1
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