SPDZi1 is a potent and selective syntenin inhibitor that binds to PDZ1 and PDZ2 domains of syntenin. SPDZi1 binds to the syntenin PDZ tandem (STNPDZ) with a Kd of 3.6 µM. SPDZi1 suppresses glioblastoma and reduces the activation of NF-kappaB, a downstream effector of syntenin[1].
Molecular Weight:
405.40
Formula:
C22H19N3O5
Target:
NF-kappaB
Application Notes:
MCE Product type: Reference compound
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