Eg5-IN-3 (5) is an Eg5 inhibitor that targets the novel allosteric pocket (alpha4/alpha6/L11). Eg5-IN-3 (5) causes tubulin assembly distortion with irregular morphology, resulting in a typical mitotic arrest similar to Monastrol (HY-101071A)[1].
Molecular Weight:
429.47
Formula:
C23H23N7O2
Target:
Kinesin,Microtubule/Tubulin
Application Notes:
MCE Product type: Reference compound
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