LYP-8 is a potent and effective NAMPT degrader with maximum degradation of 97% at 0.5 µM in SKOV-3 cells. LYP-8 shows anti-cancer activity in vivo and in vitro(Sturcture Note:(Blue: Cereblon ligand (HY-112078), Black: linker (HY-128801),Pink: Nampt inhibitor Nampt-IN-11 (HY-158689))[1].
Molecular Weight:
1051.30
Purity:
99.89
Formula:
C56H74N8O10S
Target:
NAMPT,PROTACs
Application Notes:
MCE Product type: Reference compound1
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