LLC355 is a discoidin domain receptor 1 (DDR1) ATTEC degrader. LLC355 efficiently degrades DDR1 protein with a DC50 value of 150.8 nM in non-small cell lung cancer NCI-H23 cells. LLC355 induces DDR1 degradation via lysosome-mediated autophagy. LLC355 potently inhibits cancer cell tumorigenicity, migration, and invasion[1].
Molecular Weight:
1133.69
Formula:
C63H64ClF3N10O5
Target:
ATTECs,Discoidin Domain Receptor
Application Notes:
MCE Product type: Reference compound1
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