ASM-IN-2 (Compound 46) is a potent ASM inhibitor with an IC50 value of 0.87 µM, displaying good drug-like properties. ASM-IN-2 involves in multiple antidepressant mechanisms of actionin, which are associated with a decline of ceramide. It demostrates remarkable antidepressant effects in the CUMS-induced mouse, which is promising for research in the field of antidepressant drugs[1].
Molecular Weight:
392.63
CAS Number:
[2305789-66-4]
Formula:
C16H11BrClN3O2
Target:
Phospholipase
Application Notes:
MCE Product type: Reference compound
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