SelSA is a selective, orally active inhibitor for histone deacetylase 6 (HDAC6) with IC50 of 56.9 nM. SelSA inhibits the phosphorylation of ERK1/2. SelSA inhibits the proliferation of breast cancer cells and hepatocellular carcinoma cells with IC50 of 0.58-2.6 µM, inhibits cell migration and invasion of Huh7, and induces apoptosis. SelSA exhibits antitumor activity in mouse model[1][2].
Molecular Weight:
295.24
Purity:
99.83
CAS Number:
[1225038-92-5]
Formula:
C13H16N2OSe
Target:
Apoptosis,HDAC
Application Notes:
MCE Product type: Reference compound
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