PI3Kdelta-IN-22 (Compound 26) is a selective inhibitor for PI3Kdelta with pKi of 9.3. PI3Kdelta-IN-22 inhibits PI3Kdelta-AKT signaling pathway in THP-1 cells, with pIC50 of 9.4. PI3Kdelta-IN-22 exhibits good pharmacokinetic characters in rats[1].
Molecular Weight:
586.68
Formula:
C27H35FN8O4S
Target:
PI3K
Application Notes:
MCE Product type: Reference compound
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