Leuxinostat is an inhibitor for HDAC with IC50 of 30 nM for hHDAC6. Leuxinostat inhibits the proliferation of cells THP1, K562, U937 and MEK1, induces apoptosis in leukemia cells NB4 and MOLT-4. Leuxinostat inhibits the expansion of hematopoietic stem cells and exhibits antileukemic activity in zebrafish models[1].
Molecular Weight:
356.38
Formula:
C18H20N4O4
Target:
Apoptosis,HDAC
Application Notes:
MCE Product type: Reference compound
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