COB-187 is a potent, ATP-competitive and selective inhibitor of GSK-3beta. COB-187 inhibits GSK-3 through a reversible and Cysteine (Cys)-199-dependent mechanism. COB-187 inhibits LPS induced cytokine production and SARS-CoV-2 spike protein-induced CXCL10 production[1].
Molecular Weight:
302.41
Purity:
95
CAS Number:
[1862177-86-3]
Formula:
C15H14N2OS2
Target:
GSK-3
Application Notes:
MCE Product type: Reference compound
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