OX-201 is an orally active, blood-brain barrier-permeable OX2R agonist with an EC50 of 8.0 nM. OX-201 activates OX2R to induce wakefulness and neuronal activation. OX-201 promotes the release of neuron activity-dependent tau protein from neurons into the interstitial fluid of hippocampal tissues. OX-201 is applicable to research related to Alzheimers disease and tauopathies[1].
Molecular Weight:
506.49
CAS Number:
[2460722-03-4]
Formula:
C22H23F5N2O4S
Target:
Orexin Receptor (OX Receptor),Tau Protein
Application Notes:
MCE Product type: Reference compound
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