LSD1-IN-34, CAS [[3048029-74-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-162729
Supplier Catalog Number:
HY-162729
Alternative Catalog Number:
MCE-HY-162729-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
LSD1-IN-34 (Compound 7d) is the orally active inhibitor for Lysine-specific demethylase (LSD) and monoamine oxidase (MAO), with IC50 of 4.51 and 18.46 nM, for LSD1 and MAO A. LSD1-IN-34 inhibits the Ang II-induced neonatal rat myocardial fibroblasts (NRCFs) activation, without significant toxicity (20 µM). LSD1-IN-34 inhibits TGFbeta/Smad signaling pathway, and ameliorates heart failure in mice. LSD1-IN-34 exhibits good pharmacokinetic characteristics in rats[1].
